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6 Guidance for the preparation of an Annex XV dossier on the identification of substances of very To identify CMRs, the EU Regulation on Classification, Labelling and Packaging (CLP, EC 1272/2008) has been used as a source. The CLP regulation contains a register of all officially classified substances including CMR substances in category 1A or 1B. — određivanja tvari CMR, PBT, vPvB i drugih tvari koje izazivaju jedanaku zabrinutost u skladu s člankom 59., — the identification of CMRs, PBTs , vPvBs, or a substance of equivalent concern in accordance with Article 59, ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 83 H 3C Cl Cl Cl S O O Cl Figure 1 Structural formula of a possible impurity sulfhonyl chloride, hexadecane, trichloro. It is noted, that the PBT assessment of the LCCP –fraction is presented in the PBT summary no. 110. 1.2 Physico-Chemical properties Se hela listan på baike.baidu.com 4 il s’agit là des substances qui seraient identifiées sur la liste 59.1 pour des raisons autres qu’un classement CMR 1 ou 2 au sens de la directive 67/548/CEE ou PBT ou vPvB selon les critères de l’annexe XIII mais qui susciteraient un niveau de préoccupation équivalent à celui suscité par les substances classées comme telles. PBT-criteria vPvB-criteria P* Half-life > 60 d in marine water or in freshwater* > 40 d or in marine sediment > 180 d or in freshwater sediment > 120 d Half-life > 60 d marine or freshwater or >180 d in marine or fresh water sediment B BCF > 2000 BCF > 5000 T Chronic NOEC < 0.01 mg/l or CMR ** or endocrine disrupting effects 제19409호 관 보 2018.

CMR-effekter (cancerframkallande, mutagena och reproduktionstoxiska Resultat av PBT- och vPvB-bedömningen CMR-effekter (cancerframkallande, mutagena och PBT: Persistent, Bioaccumulative and Toxic. Resultat av PBT- och vPvB-bedömningen. PBT: Ej användbar. CMR-effekter (cancerframkallande, mutagena och reproduktionstoxiska Resultat av PBT- och vPvB-bedömningen CMR-effekter (cancerframkallande, mutagena och PBT: Persistent, Bioaccumulative and Toxic. ämnen (PBT), och potentiellt väldigt persistenta och väldigt som orsakar lika stora betänkligheter som CMR-ämnen eller PBT-/vPvB-ämnen. reproduktionsstörande (CMR).

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b) Materialspåret. Andra faror. · Resultat av PBT- och vPvB-bedömningen CMR-effekter (cancerframkallande, mutagena och reproduktionstoxiska egenskaper).

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Naturskyddsföreningen anser det vara av stor vikt att bristerna som Kraven innebär bl a också en kontroll av allergiframkallande ämnen samt ämnen med särskilt hälso- och miljöfarliga egenskaper (CMR, PBT). Kopiera krav Nomenklatur. • CMR = Carcinogena, mutagena, reproduktionstoxiska. • PBT = Persistent bioaccumulative. PBT Persistent, bioaccumulative, toxic.

vPvB och sådana som ”inger motsvarande grad av betänklighet”, till exempel hormonstörande ämnen. Utgångspunkt: Ämnen med farliga egenskaper såsom CMR-ämnen, allergi- ämnen, hormonstörande samt PBT/vPvB-ämnen. b) Materialspåret. Andra faror. · Resultat av PBT- och vPvB-bedömningen CMR-effekter (cancerframkallande, mutagena och reproduktionstoxiska egenskaper).
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D4 PBT/vPvB EVALUATION completeness a literature search was meeting the criteria for being a CMR, PBT or vPvB, there is scientific evidence of probable serious effects to human health or the environment. Such substances Substances that are considered PBT (persistent, bioaccumulative and toxic) and/ or Establishment of toxicity profiles for aquatic species or according to CMR Feb 17, 2021 cancerogenic, mutagenic or toxic to reproduction (CMR), Category 1A and 1. persistent, bioaccumulative and toxic (PBT) /very persistent and Maine Department of Environmental Protection publishes list of ten food contact chemicals (FCCs) of high concern, follows state's Toxic Chemicals in Food Second, there must be scientific evidence that these effects give rise to an ELoC to those of CMR, PBT or vPvB substances. Persistence and mobility relate to a Mono-constituent substance of > 80 % (w/w), including additives (stabilisers). Additives or impurities which are classified by the EU as CMR Cat. 1 or 2, PBT or Annex XVII Entry 15.

De produkter som finns på listan har olika användningsområden som bland annat universalsmörjning, rälssmörjning, smörjning av tunga skogsmaskiner och centrala smörjsystem för lastbilar och bussar Definitionen av särskilt farliga ämnen omfattar cancerframkallande, mutagena och reproduktionsstörande ämnen (CMR), långlivade och bioackumulerande ämnen (PBT), mycket långlivade och mycket bioackumulerande ämnen (vPvB) och särskilt farliga metaller (kvicksilver, kadmium, bly och dess föreningar). Långlivade, bioackumulativa och toxiska ämnen (PBT-ämnen) eller mycket långlivade och mycket bioackumulerbara ämnen (vPvB-ämnen) i enlighet med bilaga XIII till Reach. Ämnen, från fall till fall, som orsakar lika stora betänkligheter som CMR-ämnen eller PBT-/vPvB-ämnen. Management of PBT/vPvB substances under REACH. The REACH Regulation pays specific attention to the PBT/vPvB concern.
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ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 83 H 3C Cl Cl Cl S O O Cl Figure 1 Structural formula of a possible impurity sulfhonyl chloride, hexadecane, trichloro. It is noted, that the PBT assessment of the LCCP –fraction is presented in the PBT … ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO.18 JUSTIFICATION 1 IDENTIFICATION OF THE SUBSTANCE AND PHYSICAL AND CHEMICAL PROPERTIES Name: 2-Propenoic acid, 2-methyl-, C9-11-isoalkyl esters, C10-rich EC Number: 292-128-0 CAS Number: 90552-07-1 IUPAC Name: Molecular Formula: C14H26O2 Molecular Weight: 226 Structural Formula: ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 57 1.2 PHYSICO-CHEMICAL PROPERTIES Table 1 Summary of physico-chemical properties REACH ref Annex, § Property Value Comments V, 5.1 Physical state at 20 C and 101.3 Kpa liquid V, 5.2 Melting / freezing point - V, 5.3 Boiling point - V, 5.5 Vapour pressure - 2020-01-01 ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 78 relevant pH range (ca. 4-9) in ionised form each of the molecule being either fully or partly ionised (note: four carboxylic acid groups). 2 MANUFACTURE AND USES Two companies have provided information on the substance under Regulation 93/793/EEC. ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 40 01.02.2007 4 4.1.3 Other information 1 BIOWIN v4.02 gives an overall prediction that the substance is not readily biodegradable.

PBT substances are substances that are Persistent, Bioaccumulative and Toxic (PBT). vPvB substances are substances that are very Persistent and very Bio-accumulative (vPvB). Saphira Eco is our comprehensive line of eco-friendly consumables for prepress, press and postpress. Download our catalog of criteria. Site language C) Sonstige CMR-, PBT-, vPvB-Stoffe und ähnlich besorgniserregende Stoffe (ohne harmonisierte Einstufung). 6 Guidance for the preparation of an Annex XV dossier on the identification of substances of very To identify CMRs, the EU Regulation on Classification, Labelling and Packaging (CLP, EC 1272/2008) has been used as a source. The CLP regulation contains a register of all officially classified substances including CMR substances in category 1A or 1B.
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2021-02-01 · For all subsets – CMR, PBT/vPvB and ED – there is a clear relationship observed (R 2 ranging from 0.84 to 0.89), and indicates the importance of chemical similarity for toxicological concern. Based on this relationship, 50% of the experts expect a comparable toxicological concern for a substance-pair with an average chemical similarity of around 3 in the Likert scale used for chemical A substance of very high concern is a chemical substance concerning which it has been proposed that use within the European Union be subject to authorisation under the REACH Regulation. Indeed, listing of a substance as an SVHC by the European Chemicals Agency is the first step in the procedure for authorisation or restriction of use of a chemical. The first list of SVHCs was published on 28 October 2008 and the list has been updated many times to include new candidates. The most PBT: CMR: Persistenta Cancerogena Bioackumulerande Mutagena Toxiska Reproduktionsstörande Naturfrämmande värstingar Många klor- och bromföreningar förknippas med särskilt allvarliga miljö- och hälsoeffekter. Dessa inkluderar effektkategorier som enligt rutan ovan kort brukar betecknas PBT och CMR The PBT Working Group, an official assembly of representatives from EU member states as well as experts from the former European Chemicals Bureau (ECB), had by 2008 concluded that a number of substances fulfil the EU criteria as PBT or vPvB.

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There is a strong demand for early stage identification of potential Substances of Very High Concern (SVHC). SVHCs are substances that are classified as carcinogenic, mutagenic or reprotoxic (CMR); persistent, bioaccumulative and toxic (PBT) or very persistent and very bioaccumulative (vPvB); or as substances with an equivalent level of concern, like endocrine disruption (ED). The proposal shall include the identity of substance(s) concerned and whether it is proposed to be identified as a CMR according to Article 57(a), (b) or (c), a PBT according to Article 57(d), a vPvB according to Article 57(e), or a substance of equivalent concern according to Article 57(f). cmr / pbt KREATiS is a unique organisation offering you in silico ecotoxicology, mammalian toxicology and physical chemistry predictions to screen the hazards of your substance or to complete your regulatory dossiers or boost your R&D in the most time and cost efficient way possible using: As a result, once a PBT chemical is released into the environment it will accumulate and persist in fatty tissues of animals and end up in the food chain, concentrating on the top, affecting mainly predators such as fish, predatory birds and mammals (e.g. Polar bears, seals, whales), including humans. Overview and Comparison of PBT and vPvB Criteria in EU and USA. Little Pro on 2017-05-25 Views: .

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ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 40 01.02.2007 4 4.1.3 Other information 1 BIOWIN v4.02 gives an overall prediction that the substance is not readily biodegradable. However, some degradation is expected to occur according to the models. 4.1.4 Summary and discussion of persistence Proposal for identification of a substance as a CMR, PBT, vPvB or a substance of an equivalent level of concern Substance Name: Coal tar pitch, high temperature EC Number: 266-028-2 CAS number: 65996-93-2 Submitted by : European Chemicals Agency (ECHA) Version : August 2009 Predicting PBT and CMR properties of substances of very high concern (SVHCs) using QSAR models, and application for K-REACH. Toxicol Rep. 2020 Aug 15;7:995-1000. doi: 10.1016/j.toxrep.2020.08.014. eCollection 2020. Management of PBT/vPvB substances under REACH.

These are known as PBT substances (short for Persistent, Bio-accumulative and Toxic). CMR: Cancerframkallande, Mutagent Reproduktionstoxiskt PBT / vPvB: Persistent, Bioackumulerande, Toxiskt SVHC: Substances of Very High Concern RAC: Risk Assesment Committee SEAC: Socioeconomic Committee KOM: Kommissionen MS: Medlemsstater Åtgärd 5: Främja ersättning av SVHC ämnen Åtgärd 14: Stödja små och medelstora företags efterlevnad karcinogenní, mutagenní nebo toxické pro reprodukci (CMR) klasifikované v kategorii 1 nebo 2; perzistentní, bioakumulativní a toxické (PBT) nebo vysoce perzistentní a vysoce bioakumulativní (vPvB) podle kritérií přílohy XIII nařízení REACH nebo SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 38 TC NES SUBGROUP ON IDENTIFICATION OF PBT AND VPVP SUBSTANCES RESULTS OF THE EVALUATION OF THE PBT/VPVB PROPERTIES OF: Substance name: Clofenotane (= p,pDDT) EC number: 200-024-3 CAS number: 50-29-3 Molecular formula: C14H9Cl5 Structural formula: Status: Fulfils POP criteria Overview and Comparison of PBT and vPvB Criteria in EU and USA. Little Pro on 2017-05-25 Views: . PBT substances are substances that are Persistent, Bioaccumulative and Toxic (PBT).